Description
LL‑37
A multifunctional human cathelicidin antimicrobial peptide with roles in infection defense, immune regulation, and tissue healing.
Broad-spectrum antimicrobial activity: kills Gram-positive and Gram-negative bacteria through membrane disruption; effective also against enveloped viruses and fungi mindbodyfunctionalmedicine.com+9PMC+9Frontiers+9TransformYou
Facilitates biofilm inhibition and enhances microbial clearance—low risk of resistance compared to traditional antibiotics PMC
Immunomodulatory: context-dependent pro- and anti-inflammatory effects; modulates TLR signaling, cytokine production, and macrophage activity TransformYou+3PMC+3Frontiers+3
Promotes chemotaxis and wound healing by attracting immune cells and stimulating keratinocyte migration via EGFR & FPR2 Frontiers+9PMC+9PMC+9
Enhances tissue regeneration, angiogenesis, and extracellular matrix remodeling—important in skin and mucosa repair SB PEPTIDE+7Wikipedia+7mindbodyfunctionalmedicine.com+7
Potential antiviral action (e.g., against SARS‑CoV‑2) by binding viral proteins, modulating inflammation, and preventing microthrombosis Frontiers
Ideal for applications in topical wound care, infection prevention, inflammatory regulation, and enhanced tissue repair.
